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METHOD FOR RELATIVE QUANTIFICATION OF NUCLEIC ACID

2022-12-11 来源:意榕旅游网
专利内容由知识产权出版社提供

专利名称:METHOD FOR RELATIVE QUANTIFICATION

OF NUCLEIC ACID SEQUENCE, EXPRESSION,OR COPY CHANGES, USING COMBINEDNUCLEASE, LIGATION, AND POLYMERASEREACTIONS

发明人:Francis Barany,Eugene Spier,Alain Mir申请号:US14378268申请日:20130214

公开号:US20150038336A1公开日:20150205

摘要:The present invention is directed to methods for identifying the presence ofone or more target nucleotide sequences in a sample that involve a nuclease-ligationreaction. In some embodiments, the ligation products formed in the nuclease-ligationprocess of the present invention are subsequently amplified using a polymerase chainreaction. The ligated product sequences or extension products thereof are detected, andthe presence of one or more target nucleotide sequences in the sample is identifiedbased on the detection.

申请人:CORNELL UNIVERSITY

地址:Ithaca NY US

国籍:US

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