专利名称：Transcriptional regulator发明人：Michael H. Jones申请号：US10293822申请日：20021112
公开号：US20030083470A1公开日：20030501
摘要：A database search using the sequence of transcriptional regulator RING3 havinga bromodomain identified an EST sequence that is highly homologous with RING3. Usingprimers prepared based on the EST sequence, a gene encoding a novel transcriptionalregulator having a bromodomain has been successfully isolated from a human testiscDNA library by polymerase chain reactions. The results of analysis of the isolated generevealed that this gene is expressed strongly in testis cells with a potent proliferativeability. The use of the above transcriptional regulator and its gene enables screeningcandidate compounds for factors interacting with the transcriptional regulator or drugscontrolling the activity of the regulator.
申请人：CHUGAI SEIYAKU KABUSHIKI KAISHA, A JAPAN CORPORATION
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